Activity #
BSC 1086C Human Anatomy & Physiology II
 
"85 Miles of Nephron"
 
 
 
Area of Study 
    The Urinary System
Learning Objectives 
    1. Identify the components of the urinary system, and describe the vital functions performed by the system.
    2. Describe the structural features of the kidneys.
    3. Describe the structure of the nephron and the processes involved in the formation of urine.
    4. Identify the major blood vessels associated with each kidney, and trace the path of blood flow through a kidney.
    5. List and describe the factors that influence filtration pressure and the rate of filtrate formation.
    6. Describe the structures and functions of the ureters, urinary bladder, and urethra.
    7. Discuss the voluntary and involuntary regulation of urination and details of the micturition reflex.
    8. Describe the effects of aging on the urinary system.

Part A  Functional Anatomy of the Nephron

    1. Each pair will be assigned a segment of the nephron. 

    2. Describe the anatomical structure of the nephron, the histology of its cells, and the role it plays in urine production. 

    3. Describe its major role as filtration, reabsorption or secretion. 

    4. With each segment of the nephron, a regulatory mechanism is listed.  Describe the physiological response of that system. 

    5. Use pictures to depict the action.
     

      Renal Corpuscle (glomerulus, afferent and efferent arterioles)
      Impact of a decline in systemic blood pressure
      Atrial Natriuretic Peptide

      Proximal Convoluted Tubule and Peritubular Capillaries
      How does reabsorption occur? 
      What is reabsorbed?  How?

      Loop of Henle (descending and ascending)
      Counter current multiplication
      Vasa Recta

      Distal Convoluted Tubule and Juxtaglomerular Apparatus
      JGA and Renin Secretion
      PTH and Calcitriol
      Secretion:  of what?  How?

      Connecting tubules, Collecting ducts and Papillary duct
      Aldosterone
      Antidiuretic Hormone
      Reabsorption:  of what?  How?

      Each autonomic event and reaction should be paired up. 


Part B Trace the path of    ________ through the nephron

    1. Each pair of students will be given a molecule.  

    2. Trace the path of the molecule through the nephron.  

    3. Describe what happens to that molecule at each section of the nephron.
     

      1. Calcium
      2. Glucose
      3. Protein
      4. Sodium
      5. Choride
      6. Potassium
      7. Water
      8. Hydrogen ions
      9. Urea
      10. Ammonium

      A poster describing the event and reaction as identified above.
     

 
 
 
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