|
Innate Immunity
|
Description
|
Answer
|
| a. Interleukin 1 (IL-1a,IL-1b) |
1. Stimulates proliferation and differentation; induces
class switch to IgA |
- |
| b. Interleukin 2 (IL-2) |
2. Suppresses cytokine production and thus indirectly
reduces cytokine production by TH1 cells |
- |
| c. Interleukin 3 (IL-3) |
3. Inhibits activation and release of inflammatory
cytokines; important regulator of inflammatory response. |
- |
| d. Interleukin 4 (IL-4) |
4. Acts synergistically with IL-2 to induce differentation
into CTLs. Stimulates proliferation of NK, LAK, and activated TH1
cells |
- |
| e. interleukin 5 |
5. Co-stimulates activation TH. Promotes
maturation and clonal expansion of B-cells. |
- |
| f. Interleukin 6 |
6. Co-stimulates activation of B-cells. Stimulates
proliferation and differentiation; induces class switch to IgG1 and IgE. |
- |
| g. Interleukin 8 (IL-8) |
7. Supports growth and differentiation of hematopoietic
cells. Stimulates growth and histamine secretion from Mast cells. |
- |
| h. Interleukin 10 (IL-10) |
8. Promotes terminal differentiation of B-cells into plasma
cells. Induces synthesis of acute-phase proteins. |
- |
| i. Interleukin 12 (IL-12) |
9. Chemokine; chemotactically attracts; induces adherence
to vascular endothelium and extravasation into tissues. |
- |
| j. Interleukin 13 (IL-13) |
- |
- |
