Wuchereria bancrofti

Lymphatic filariasis: adults of B. malayi and W. bancrofti live in the lymphatic vessels and lymphnodes where they cause dilatation, inflammatory infiltrates and, at last, blockage of the lymphatic circulation. Adenolymphangitis, orchitis, epididymitis associated with fever are the commonest manifestations of the acute stage of the infection; eosinophilia is frequent at this stage. Lymphoedema particularly of the legs and scrotum, hydrocoeles and chyluria are the result of the progression of the disease; genital manifestations are frequent in W. bancrofti infections while they are rare during B. malayi infections. Lymphatic filariasis: elephantiasis of scrotum.